THBS2

Description		thrombospondin 2
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GO Annotations	Cellular Component	Extracellular Region Basement Membrane Platelet Alpha Granule Collagen-containing Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Heparin Binding
	Biological Process	Cell Adhesion Negative Regulation Of Angiogenesis Positive Regulation Of Synapse Assembly
Pathways		Signaling by PDGF Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Anorectal malformation ( 31136621) Blood protein levels ( 30072576 29875488) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Carotid intima media thickness x smoking interaction ( 32117412) Central corneal thickness ( 32528159 29760442) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Copper levels ( 26025379) Dimensional psychopathology (Cognitive) ( 29496196) Haemorrhoidal disease ( 33888516) Joint mobility (Beighton score) ( 27182965) Liver disease severity in Alagille syndrome ( 28090565) Obesity-related traits ( 23251661) Pulse pressure ( 28135244 27841878)
Interacting Genes		4 interacting genes: MMP2 MMP9 RPS6KA2 THBS3
Entrez ID		7058
HPRD ID		01766
Ensembl ID		ENSG00000186340
Uniprot IDs		P35442
PDB IDs		1YO8 2RHP
Enriched GO Terms of Interacting Partners?
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