TAPBP

Description		TAP binding protein
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding ABC-type Peptide Antigen Transporter Activity MHC Class I Protein Binding Peptide Antigen Binding TAP1 Binding TAP2 Binding Unfolded Protein Binding TAP Complex Binding
	Biological Process	MHC Class I Protein Complex Assembly MHC Class Ib Protein Complex Assembly Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Immune Response Regulation Of Gene Expression Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Stabilization Regulation Of Protein Complex Stability Protein-containing Complex Assembly
Pathways		ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576 29875488)
Interacting Genes		10 interacting genes: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2 TNF UBC
Entrez ID		6892
HPRD ID		09061
Ensembl ID		ENSG00000231925
Uniprot IDs		A0A024RCT1 A0A0A0MSV9 A0A0A0MT98 O15533
PDB IDs		3F8U 6ENY
Enriched GO Terms of Interacting Partners?
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