STIM1

Description		stromal interaction molecule 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Microtubule Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Cortical Endoplasmic Reticulum Sarcoplasmic Reticulum Membrane Plasma Membrane Raft
	Molecular Function	Protease Binding Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Store-operated Calcium Entry Detection Of Calcium Ion Cellular Calcium Ion Homeostasis Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Angiogenesis Regulation Of Calcium Ion Transport Enamel Mineralization Regulation Of Store-operated Calcium Entry
Pathways		Elevation of cytosolic Ca2+ levels Ion homeostasis Ion homeostasis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Calcium levels ( 29403010) Disruptive behavior disorder and attention deficit hyperactivity disorder ( 33495439) Hemoglobin ( 32888494) Malaria ( 31844061) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252) Systemic lupus erythematosus ( 33272962) Waist circumference ( 34074324)
Interacting Genes		7 interacting genes: IFNGR1 INSIG2 RABAC1 RRM1 SLC7A1 STIM2 TH
Entrez ID		6786
HPRD ID		05803
Ensembl ID		ENSG00000167323
Uniprot IDs		G0XQ39 Q13586
PDB IDs		2K60 2MAJ 2MAK 3TEQ 4O9B 6YEL
Enriched GO Terms of Interacting Partners?
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