SLC12A1

Description		solute carrier family 12 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Sodium:potassium:chloride Symporter Activity Potassium:chloride Symporter Activity
	Biological Process	Ion Transport Cell Volume Homeostasis Ion Transmembrane Transport Sodium Ion Transmembrane Transport Chloride Ion Homeostasis Potassium Ion Homeostasis Sodium Ion Homeostasis Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Cation-coupled Chloride cotransporters Defective SLC12A1 causes Bartter syndrome 1 (BS1)
Drugs		Torasemide Methyclothiazide Chlorthalidone Chlormerodrin Furosemide Potassium chloride Hydroflumethiazide Bumetanide Etacrynic acid Quinethazone Piretanide
Diseases
GWAS		Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Metabolite levels (Pyroglutamine) ( 23934736) Systemic lupus erythematosus ( 26606652)
Interacting Genes		3 interacting genes: OXSR1 STK39 TCF12
Entrez ID		6557
HPRD ID		02908
Ensembl ID		ENSG00000074803
Uniprot IDs		B4DPF4 Q13621 Q8IUN5
PDB IDs
Enriched GO Terms of Interacting Partners?
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