SLAMF1

Description		signaling lymphocytic activation molecule family member 1
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GO Annotations	Cellular Component	External Side Of Plasma Membrane Integral Component Of Membrane Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Virus Receptor Activity Antigen Binding Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity SH2 Domain Binding Identical Protein Binding
	Biological Process	Natural Killer Cell Differentiation Natural Killer Cell Proliferation Leukocyte Chemotaxis Involved In Inflammatory Response Adaptive Immune Response Myeloid Dendritic Cell Activation Involved In Immune Response Negative Regulation Of T Cell Cytokine Production Phagocytosis Cell Adhesion Positive Regulation Of Cell Population Proliferation Positive Regulation Of Macrophage Chemotaxis Regulation Of Vesicle Fusion Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Activated T Cell Proliferation Innate Immune Response Positive Regulation Of JNK Cascade Viral Entry Into Host Cell Regulation Of Catalytic Activity Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of CD40 Signaling Pathway Positive Regulation Of Dendritic Cell Chemotaxis Positive Regulation Of T-helper 1 Cell Cytokine Production
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Memory decline ( 31985465) Microalbuminuria ( 26631737) Multiple sclerosis ( 31604244) Schizophrenia (treatment resistant) ( 22479419)
Interacting Genes		7 interacting genes: FGR FYN INPP5D PAX6 PTPN11 SH2D1A SH2D1B
Entrez ID		6504
HPRD ID		04603
Ensembl ID		ENSG00000117090
Uniprot IDs		Q13291
PDB IDs		1D4T 1D4W 1I3Z 1KA6 1KA7 1M27 2DZF 2IE9 2IFL 2IG5
Enriched GO Terms of Interacting Partners?
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