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POLD4
Description
DNA polymerase delta 4, accessory subunit
Image
GO Annotations
Cellular Component
Nucleoplasm
Delta DNA Polymerase Complex
Molecular Function
DNA-directed DNA Polymerase Activity
Protein Binding
Biological Process
DNA Synthesis Involved In DNA Repair
DNA-dependent DNA Replication
Pathways
Recognition of DNA damage by PCNA-containing replication complex
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Removal of the Flap Intermediate from the C-strand
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand
Drugs
Diseases
GWAS
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Interacting Genes
9 interacting genes:
DTL
PCNA
POLD1
POLD2
POLD3
POLE
RNF8
SEC23IP
WRNIP1
Entrez ID
57804
HPRD ID
17873
Ensembl ID
ENSG00000175482
Uniprot IDs
A0A024R5D7
Q6NSD7
Q9HCU8
PDB IDs
6HVO
6S1M
6S1N
6S1O
6TNY
6TNZ
Enriched GO Terms of Interacting Partners
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