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TIGAR

Description TP53 induced glycolysis regulatory phosphatase
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Mitochondrial Outer Membrane
  • Cytosol
Molecular Function
  • Bisphosphoglycerate 2-phosphatase Activity
  • Fructose-2,6-bisphosphate 2-phosphatase Activity
  • Protein Binding
Biological Process
  • Response To Ischemia
  • Fructose 2,6-bisphosphate Metabolic Process
  • Autophagy
  • Apoptotic Process
  • Cellular Response To DNA Damage Stimulus
  • Response To Xenobiotic Stimulus
  • Response To Gamma Radiation
  • Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
  • Dephosphorylation
  • Fructose 1,6-bisphosphate Metabolic Process
  • Negative Regulation Of Programmed Cell Death
  • Regulation Of Pentose-phosphate Shunt
  • Positive Regulation Of DNA Repair
  • Negative Regulation Of Glycolytic Process
  • Intestinal Epithelial Cell Development
  • Cellular Response To Cobalt Ion
  • Cellular Response To Hypoxia
  • Negative Regulation Of Neuron Death
  • Negative Regulation Of Mitophagy
  • Regulation Of Response To DNA Damage Checkpoint Signaling
  • Positive Regulation Of Hexokinase Activity
  • Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
  • Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
  • TP53 Regulates Metabolic Genes
Drugs
Diseases
GWAS
Interacting Genes 2 interacting genes: APP RPL11
Entrez ID 57103
HPRD ID 12610
Ensembl ID ENSG00000078237
Uniprot IDs Q9NQ88
PDB IDs 3DCY
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025