DUSP22

Description		dual specificity phosphatase 22
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Filamentous Actin Leading Edge Of Lamellipodium
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity Protein Tyrosine Kinase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cell Migration Peptidyl-tyrosine Dephosphorylation Regulation Of Cell Population Proliferation Positive Regulation Of JNK Cascade Negative Regulation Of Focal Adhesion Assembly Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity
Pathways
Drugs
Diseases
GWAS		Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081) Albumin-globulin ratio ( 29403010) Alopecia areata ( 25608926) Asthma (childhood onset) ( 31036433) Crohn's disease ( 26192919) Eosinophil counts ( 32888494) Inflammatory bowel disease ( 26192919) Male-pattern baldness ( 28196072) Non-albumin protein levels ( 29403010) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 33536424) Takayasu arteritis ( 30498034)
Interacting Genes		5 interacting genes: HOXA1 MAP2K4 MAP2K7 MAPK14 MAPK8
Entrez ID		56940
HPRD ID		13255
Ensembl ID		ENSG00000112679
Uniprot IDs		A0A384NLC8 Q9NRW4
PDB IDs		1WRM 4WOH 6L1S 6LMY 6LOT 6LOU 6LVQ 7C8S
Enriched GO Terms of Interacting Partners?
Tagcloud ?