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SPIRE1

Description spire type actin nucleation factor 1
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytosol
  • Cytoskeleton
  • Cell Cortex
  • Cytoplasmic Vesicle Membrane
  • Integral Component Of Mitochondrial Outer Membrane
  • Cleavage Furrow
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Actin Binding
  • Protein Binding
Biological Process
  • Protein Transport
  • Vesicle-mediated Transport
  • Actin Cytoskeleton Organization
  • Actin Filament Polymerization
  • Cleavage Furrow Formation
  • Polar Body Extrusion After Meiotic Divisions
  • Actin Nucleation
  • Intracellular Transport
  • Golgi Vesicle Transport
  • Establishment Of Meiotic Spindle Localization
  • Actin Filament Network Formation
  • Formin-nucleated Actin Cable Assembly
  • Positive Regulation Of Mitochondrial Fission
  • Positive Regulation Of Double-strand Break Repair
Pathways
Drugs
Diseases
GWAS
  • Carotid plaque burden ( 28282560)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Red blood cell count ( 32888494)
Interacting Genes 4 interacting genes: BBS4 CEP192 ETS1 PLEKHA5
Entrez ID 56907
HPRD ID 11600
Ensembl ID ENSG00000134278
Uniprot IDs Q08AE8
PDB IDs 2YLE 2YLF 3R7G 3RBW
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025