PRLR

Description		prolactin receptor
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Endosome Lumen Receptor Complex
	Molecular Function	Cytokine Receptor Activity Leukemia Inhibitory Factor Receptor Activity Oncostatin-M Receptor Activity Prolactin Receptor Activity Ciliary Neurotrophic Factor Receptor Binding Protein Binding Peptide Hormone Binding Cytokine Binding Metal Ion Binding
	Biological Process	Steroid Biosynthetic Process Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Embryo Implantation Lactation Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Prolactin Signaling Pathway Oncostatin-M-mediated Signaling Pathway Activation Of Janus Kinase Activity Negative Regulation Of Apoptotic Process Leukemia Inhibitory Factor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis
Pathways		Prolactin receptor signaling Prolactin receptor signaling Growth hormone receptor signaling
Drugs		Somatotropin
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Chronotype ( 30696823) Metabolite levels ( 23823483) Paneth cell defects in Crohn's disease ( 28352666) Psychotic experience ( 31553412) Response to lurasidone in schizophrenia ( 29730043)
Interacting Genes		22 interacting genes: CISH CREBBP CSH1 FBXW11 GH1 ICAM3 INSIG2 JAK2 MFGE8 NEK3 PLPP6 PPIA PRL PTPN11 SOCS2 SOCS3 TEC VAV1 VAV2 YWHAG YWHAZ ZAP70
Entrez ID		5618
HPRD ID		01457
Ensembl ID		ENSG00000113494
Uniprot IDs		P16471
PDB IDs		1BP3 2LFG 2N7I 3D48 3MZG 3N06 3N0P 3NCB 3NCC 3NCE 3NCF 4I18
Enriched GO Terms of Interacting Partners?
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