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PAF1

Description PAF1 homolog, Paf1/RNA polymerase II complex component
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytoplasm
  • Membrane
  • Cdc73/Paf1 Complex
  • Cell Junction
  • Transcriptionally Active Chromatin
Molecular Function
  • RNA Polymerase II Complex Binding
  • Chromatin Binding
  • Protein Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Endodermal Cell Fate Commitment
  • Transcription Elongation From RNA Polymerase II Promoter
  • MRNA Polyadenylation
  • Histone Monoubiquitination
  • Wnt Signaling Pathway
  • Nucleosome Positioning
  • Stem Cell Population Maintenance
  • Positive Regulation Of Histone Methylation
  • Positive Regulation Of MRNA 3'-end Processing
  • Histone H2B Ubiquitination
  • Protein Localization To Nucleus
  • Negative Regulation Of Myeloid Cell Differentiation
  • Cellular Response To Lipopolysaccharide
  • Positive Regulation Of Cell Cycle G1/S Phase Transition
Pathways
  • Formation of RNA Pol II elongation complex
  • RNA Polymerase II Pre-transcription Events
  • RNA Polymerase II Transcription Elongation
  • E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Interacting Genes 18 interacting genes: ENO1 ERCC6 EXOSC5 FXR2 H1-2 H3C1 HSPB1 KAT8 KMT2A MLLT1 MSL1 MSL2 MSL3 RERE RNF20 SUMO2 TCEA1 TULP3
Entrez ID 54623
HPRD ID 10140
Ensembl ID ENSG00000006712
Uniprot IDs A0A024R0H6 Q8N7H5
PDB IDs 4M6T 5ZYQ 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025