PECAM1

Description		platelet and endothelial cell adhesion molecule 1
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Secretory Granule Membrane Platelet Alpha Granule Membrane Protein-containing Complex Membrane Raft Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Phagocytosis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Leukocyte Cell-cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway Cell Recognition Positive Regulation Of Cell Migration Maintenance Of Blood-brain Barrier Monocyte Extravasation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Diapedesis Establishment Of Endothelial Barrier Bicellular Tight Junction Assembly Glomerular Endothelium Development Neutrophil Extravasation Cell-cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Positive Regulation Of Protein Localization To Cell-cell Junction
Pathways		Platelet degranulation Cell surface interactions at the vascular wall PECAM1 interactions Integrin cell surface interactions Platelet sensitization by LDL Neutrophil degranulation
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254 29212778 33020668) Myocardial infarction ( 33532862) Pulse pressure ( 27841878 30578418) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Systolic blood pressure ( 27841878)
Interacting Genes		24 interacting genes: BRIP1 CD38 CSK CTNNB1 DSP EFNB2 FOXJ1 FYN HCK INPP5D ITGA5 ITGB3 JUP LCK LYN PIK3R1 PLCG1 PRKCE PRPF40A PTPN11 PTPN6 SRC XRCC6 YES1
Entrez ID		5175
HPRD ID		01425
Ensembl ID		ENSG00000261371
Uniprot IDs		P16284
PDB IDs		2KY5 5C14 5GNI
Enriched GO Terms of Interacting Partners?
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