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PCNT

Description pericentrin
Image No pdb structure
GO Annotations Cellular Component
  • Centrosome
  • Centriole
  • Cytosol
  • Microtubule
  • Membrane
  • Centriolar Satellite
Molecular Function
  • Protein Binding
  • Calmodulin Binding
  • Molecular Adaptor Activity
Biological Process
  • Microtubule Cytoskeleton Organization
  • Mitotic Spindle Organization
  • Signal Transduction
  • Cilium Assembly
  • Positive Regulation Of Intracellular Protein Transport
Pathways
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
  • Chaperone Mediated Autophagy
  • Late endosomal microautophagy
  • Aggrephagy
  • Aggrephagy
Drugs
Diseases
GWAS
  • Heel bone mineral density ( 30598549)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • S100 calcium-binding protein levels ( 33227023)
  • Treatment resistant depression ( 30468137)
Interacting Genes 21 interacting genes: AKAP9 CALM1 CALM2 CCP110 CDK12 CEP55 COL6A1 DISC1 HPRT1 NDUFV3 PCM1 PDE9A PFKL PKNOX1 RAC3 S100B SH3BGR TP53BP1 TUBG1 TUBGCP2 TUBGCP3
Entrez ID 5116
HPRD ID 05804
Ensembl ID ENSG00000160299
Uniprot IDs O95613
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025