APIP

Description		APAF1 interacting protein
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity
	Biological Process	Apoptotic Process L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptosis Regulation Of ERK1 And ERK2 Cascade
Pathways		Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010 33339817) Lung disease severity in cystic fibrosis ( 26417704) Prostate-specific antigen levels ( 28139693) Systemic lupus erythematosus ( 19838195)
Interacting Genes		19 interacting genes: APAF1 BAZ2B CFAP206 GORASP2 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 ZBTB25
Entrez ID		51074
HPRD ID		14725
Ensembl ID		ENSG00000149089
Uniprot IDs		Q96GX9
PDB IDs		4M6R
Enriched GO Terms of Interacting Partners?
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