TNFRSF11B

Description		TNF receptor superfamily member 11b
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Extracellular Matrix
	Molecular Function	Cytokine Activity Protein Binding Signaling Receptor Activity
	Biological Process	Skeletal System Development Apoptotic Process Signal Transduction Response To Nutrient Response To Xenobiotic Stimulus Extracellular Matrix Organization Response To Magnesium Ion Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Response To Estrogen Negative Regulation Of Bone Resorption Response To Arsenic-containing Substance
Pathways		TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Asthma ( 29273806) Asthma (childhood onset) ( 30929738) Blood protein levels ( 30072576) Blood protein levels in cardiovascular risk ( 28369058) Bone mineral density ( 24249740 18455228 23437003) Bone mineral density (hip) ( 27311723 19801982) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (spine) ( 19801982) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494) Femoral neck bone mineral density ( 29499414) Heel bone mineral density ( 30598549 28869591) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lumbar spine bone mineral density ( 29499414 22504420) Lumbar spine bone mineral density (integral) ( 27476799) Lumbar spine bone mineral density (trabecular) ( 27476799) Medication use (thyroid preparations) ( 31015401) Metabolite levels ( 23823483) Osteoporosis-related phenotypes ( 20548944) Osteoprotegerin levels ( 25080503) Physiological traits ( 31902109) Serum alkaline phosphatase levels ( 33547301 31666285 29403010) Serum sclerostin levels ( 31170332) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 21980299)
Interacting Genes		7 interacting genes: FN1 THBS1 TNFSF10 TNFSF11 TNFSF13 VTN VWF
Entrez ID		4982
HPRD ID		04032
Ensembl ID		ENSG00000164761
Uniprot IDs		O00300
PDB IDs		3URF
Enriched GO Terms of Interacting Partners?
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