ARG2

Description		arginase 2
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Arginase Activity Protein Binding Manganese Ion Binding
	Biological Process	Urea Cycle Ureteric Bud Development Adaptive Immune Response Negative Regulation Of Type 2 Immune Response Nitric Oxide Biosynthetic Process Striated Muscle Contraction Arginine Catabolic Process To Ornithine Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Tumor Necrosis Factor Production Innate Immune Response Negative Regulation Of Macrophage Inflammatory Protein 1 Alpha Production Negative Regulation Of Chemokine (C-C Motif) Ligand 4 Production Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production Negative Regulation Of Defense Response To Bacterium Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Activated CD8-positive, Alpha-beta T Cell Apoptotic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Cellular Senescence
Pathways		Urea cycle
Drugs		Arginine Ornithine S-2-(Boronoethyl)-L-Cysteine
Diseases
GWAS
Interacting Genes		3 interacting genes: ARG1 DCC STK11
Entrez ID		384
HPRD ID		00143
Ensembl ID		ENSG00000081181
Uniprot IDs		A0A024R6A0 P78540
PDB IDs		1PQ3 4HZE 4I06 4IE2 4IE3 4IXU 4IXV 6Q37 6Q39 6SS2 6SS4 6SS6
Enriched GO Terms of Interacting Partners?
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