IREB2

Description		iron responsive element binding protein 2
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Binding Aconitate Hydratase Activity Protein Binding Iron-responsive Element Binding Translation Repressor Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Tricarboxylic Acid Cycle Citrate Metabolic Process Protoporphyrinogen IX Biosynthetic Process Iron Ion Transport Cellular Iron Ion Homeostasis Post-embryonic Development Negative Regulation Of Translation Osteoclast Differentiation Erythrocyte Homeostasis Intestinal Absorption Iron Ion Homeostasis
Pathways		Iron uptake and transport
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Chronic bronchitis and chronic obstructive pulmonary disease ( 25241909) Chronic obstructive pulmonary disease ( 25241909 22080838 20173748) Current cigarettes per day in chronic obstructive pulmonary disease ( 29767774) Diffusing capacity of carbon monoxide ( 30694715) Emotional recognition ( 31596458) Emphysema distribution in smoking ( 27669027) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Pre bronchodilator FEV1 ( 26634245) Pulmonary artery enlargement and chronic obstructive pulmonary disease ( 25101718) Pulmonary artery enlargement in chronic obstructive pulmonary disease ( 25101718) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: APP RBCK1 TERT USP53 YBX1
Entrez ID		3658
HPRD ID		08858
Ensembl ID		ENSG00000136381
Uniprot IDs		D3DW85 P48200
PDB IDs		6VCD
Enriched GO Terms of Interacting Partners?
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