ABR

Description		ABR activator of RhoGEF and GTPase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Axon Dendritic Spine Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Modulation Of Chemical Synaptic Transmission Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Total cholesterol levels ( 30498476)
Interacting Genes		8 interacting genes: ADRA1A APP C1QBP ECT2 ERBIN HRAS LNX1 PJA1
Entrez ID		29
HPRD ID		02649
Ensembl ID		ENSG00000159842
Uniprot IDs		B7Z2X0 B7Z683 B7Z7Z1 Q12979 Q6ZT60
PDB IDs
Enriched GO Terms of Interacting Partners?
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