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GPR18

Description G protein-coupled receptor 18
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Integral Component Of Membrane
  • Cytoplasmic Vesicle Membrane
Molecular Function
  • G Protein-coupled Receptor Activity
Biological Process
  • CD8-positive, Alpha-beta Intraepithelial T Cell Differentiation
  • CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation
  • Negative Regulation Of Leukocyte Chemotaxis
  • G Protein-coupled Receptor Signaling Pathway
  • Negative Regulation Of Tumor Necrosis Factor Production
  • Positive Regulation Of Rho Protein Signal Transduction
  • Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways
  • Class A/1 (Rhodopsin-like receptors)
  • G alpha (i) signalling events
Drugs
  • Glycine
  • Cannabidiol
  • Medical Cannabis
  • Nabiximols
Diseases
GWAS
  • Asthma ( 31959851 31619474)
  • Inflammatory bowel disease ( 28067908 23128233)
Interacting Genes 1 interacting genes: JUN
Entrez ID 2841
HPRD ID 03621
Ensembl ID ENSG00000125245
Uniprot IDs H9NIM1 Q14330
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025