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GFI1
Description
growth factor independent 1 transcriptional repressor
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nuclear Matrix
Nuclear Body
Transcription Repressor Complex
Molecular Function
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Calcidiol 1-monooxygenase Activity
Negative Regulation Of Vitamin D Biosynthetic Process
Negative Regulation Of Neuron Projection Development
Viral Process
Hemopoiesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Toll-like Receptor Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Regulation Of Histone H3-K4 Methylation
Positive Regulation Of Interleukin-6-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Pathways
Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Multiple sclerosis (
31604244
)
Multiple sclerosis and type 2 diabetes (pleiotropy) (
26920376
)
Systemic lupus erythematosus (
28714469
)
Total cholesterol levels (
33339817
)
Interacting Genes
8 interacting genes:
CSDE1
FBXW7
GSK3B
PIAS3
PICK1
RUNX1T1
SLC9A3R1
SPI1
Entrez ID
2672
HPRD ID
07527
Ensembl ID
ENSG00000162676
Uniprot IDs
Q99684
PDB IDs
Enriched GO Terms of Interacting Partners
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