FBXO5

Description		F-box protein 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Spindle Cytosol Meiotic Spindle
	Molecular Function	Protein Binding Anaphase-promoting Complex Binding Protein Kinase Binding Metal Ion Binding Ubiquitin Ligase Inhibitor Activity
	Biological Process	Oocyte Maturation Regulation Of DNA Replication Spindle Assembly Involved In Female Meiosis I Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Population Proliferation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle Organization Protein Ubiquitination Negative Regulation Of DNA Endoreduplication Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Meiotic Nuclear Division Negative Regulation Of Mitotic Metaphase/anaphase Transition Microtubule Polymerization Cell Division Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Biomineral Tissue Development Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Mesenchymal Stem Cell Migration Negative Regulation Of Cellular Senescence Negative Regulation Of Response To DNA Damage Stimulus
Pathways		SCF-beta-TrCP mediated degradation of Emi1 Regulation of APC/C activators between G1/S and early anaphase Phosphorylation of Emi1 Mitotic Metaphase/Anaphase Transition G1/S-Specific Transcription
Drugs
Diseases
GWAS		Body mass index ( 26426971) Chronotype ( 30696823) Morning person ( 30696823) Prostate cancer ( 23535732)
Interacting Genes		13 interacting genes: ANAPC1 ANAPC11 ANAPC5 ANAPC7 CDC16 CDC20 CDC23 CDK1 EVI5 FZR1 SKP1 SRC TPM3
Entrez ID		26271
HPRD ID		09348
Ensembl ID		ENSG00000112029
Uniprot IDs		Q9UKT4
PDB IDs		2M6N 4UI9
Enriched GO Terms of Interacting Partners?
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