GABRB2

Description		gamma-aminobutyric acid type A receptor subunit beta2
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle Membrane Chloride Channel Complex Neuron Projection Synapse Extracellular Exosome GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane GABA-A Receptor Complex
	Molecular Function	GABA-A Receptor Activity Inhibitory Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity GABA Receptor Activity GABA-gated Chloride Ion Channel Activity Neurotransmitter Receptor Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Sensory Perception Of Sound Ion Transmembrane Transport Regulation Of Membrane Potential Negative Regulation Of Neuron Apoptotic Process Nervous System Process Synaptic Transmission, GABAergic Regulation Of Postsynaptic Membrane Potential Inner Ear Receptor Cell Development Innervation Cellular Response To Histamine Cochlea Development Chloride Transmembrane Transport Inhibitory Synapse Assembly
Pathways		Signaling by ERBB4 GABA receptor activation GABA receptor activation
Drugs		Lorazepam Ethchlorvynol Enflurane Temazepam Butabarbital Butalbital Phenytoin Etomidate Talbutal Pentobarbital Clobazam Meprobamate Carisoprodol Eszopiclone Alprazolam Metharbital Chlordiazepoxide Amoxapine Adinazolam Lamotrigine Medroxyprogesterone acetate Clorazepic acid Acamprosate Midazolam Flurazepam Isoflurane Primidone Halazepam Propofol Propofol Diazepam Oxazepam Triazolam Ethanol Methoxyflurane Memantine Clonazepam Methyprylon Halothane Desflurane Flumazenil Estazolam Sevoflurane Ginkgo biloba Glutethimide Camazepam Delorazepam Flunitrazepam Ethyl loflazepate Cloxazolam Bromazepam Clotiazepam Fludiazepam Ketazolam Prazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Fospropofol Brotizolam Stiripentol Etizolam Thiocolchicoside Brexanolone Apalutamide Remimazolam Benzodiazepine Pinazepam Medazepam Loprazolam Doxefazepam Lormetazepam Nordazepam Oxazepam acetate Cinazepam Bentazepam Mexazolam
Diseases
GWAS		Multisite chronic pain ( 33830993 31194737) Nicotine dependence symptom count ( 25555482) Perceived intensity of sweet substances ( 31005972) Plasma neurofilament light levels ( 29747637) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483)
Interacting Genes		5 interacting genes: ARFGEF2 PPP3CA PRKCB TRAK2 UBQLN1
Entrez ID		2561
HPRD ID		02578
Ensembl ID		ENSG00000145864
Uniprot IDs		P47870
PDB IDs		6D6T 6D6U 6X3S 6X3T 6X3U 6X3V 6X3W 6X3X 6X3Z 6X40
Enriched GO Terms of Interacting Partners?
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