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GABPA

Description GA binding protein transcription factor subunit alpha
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
  • Nucleoplasm
Molecular Function
  • Transcription Cis-regulatory Region Binding
  • RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
  • Chromatin Binding
  • DNA-binding Transcription Factor Activity
  • Protein Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Blastocyst Formation
  • Regulation Of Transcription By RNA Polymerase II
  • Positive Regulation Of Gene Expression
  • Cell Differentiation
  • Negative Regulation Of Megakaryocyte Differentiation
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Cellular Response To Dopamine
Pathways
  • Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS
  • Glaucoma (primary open-angle) ( 33627673)
  • Gout (normal type) ( 32238385)
  • Nicotine dependence symptom count ( 25555482)
Interacting Genes 15 interacting genes: APP ATF1 CREBBP EP300 GABPB1 GABPB2 HCFC1 MED1 OGT PINX1 SP1 SP3 STK16 TMPRSS15 ZC2HC1B
Entrez ID 2551
HPRD ID 11793
Ensembl ID ENSG00000154727
Uniprot IDs A8IE48 Q06546 Q8IYS3
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025