IPMK

Description		inositol polyphosphate multikinase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Inositol-1,4,5-trisphosphate 6-kinase Activity Inositol Tetrakisphosphate 3-kinase Activity Inositol Tetrakisphosphate 6-kinase Activity Protein Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity Metal Ion Binding Phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Inositol Tetrakisphosphate 5-kinase Activity Inositol Tetrakisphosphate Kinase Activity Phosphatidylinositol-3,4-bisphosphate 5-kinase Activity Flavonoid Binding Myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase Activity
	Biological Process	Phosphorylation Inositol Trisphosphate Metabolic Process Inositol Phosphate Biosynthetic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphate Biosynthetic Process Necroptotic Process
Pathways		Synthesis of IPs in the nucleus
Drugs
Diseases
GWAS		Cerebrospinal fluid clusterin levels ( 26545630) Coronary artery calcification ( 23870195) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Metabolite levels ( 23823483) Monocyte count ( 32888494) Nonsyndromic cleft lip with or without cleft palate x sex interaction (2df test) ( 30277614) Obesity-related traits ( 23251661) Plasma anti-thyroglobulin levels ( 29678681)
Interacting Genes		2 interacting genes: HSF2BP TRAF6
Entrez ID		253430
HPRD ID		17153
Ensembl ID		ENSG00000151151
Uniprot IDs		Q8NFU5
PDB IDs		5W2G 5W2H 5W2I 6E7F 6M88 6M89 6M8A 6M8B 6M8C 6M8D 6M8E
Enriched GO Terms of Interacting Partners?
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