ASTN2

Description		astrotactin 2
Image
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Cell Cortex Integral Component Of Membrane Clathrin-coated Vesicle Perikaryon Cell Pole
	Molecular Function	Calcium Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding
	Biological Process	Neuron Migration Neuron Cell-cell Adhesion Protein Transport Establishment Of Body Hair Planar Orientation Negative Regulation Of Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder and schizophrenia ( 20889312) Body mass index ( 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Caudal middle frontal gyrus volume ( 31530798) Chronic obstructive pulmonary disease ( 30804561) Dentate gyrus granule cell layer volume ( 30279459) Depression ( 29700475) Drug-induced liver injury (isoniazid-containing anti-tuberculosis drugs) ( 33135175) Economic and political preferences (fairness) ( 22566634) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Feeling guilty ( 29500382) FEV1 ( 30804560) Glomerular filtration rate (creatinine) ( 28452372) Glucose homeostasis traits ( 25524916) Headache ( 29397368) Heel bone mineral density ( 30598549) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hip shape (DXA scan) ( 30320955) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 22504421) Idiopathic osteonecrosis of the femoral head ( 28000841) Immune response to anthrax vaccine ( 22658931) Lifetime average cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Lung function (FEV1/FVC) ( 28166213 26635082 30804560) Medication use (antimigraine preparations) ( 31015401) Metabolite levels ( 23823483) Migraine ( 22683712 27182965 27322543) Migraine - clinic-based ( 23793025) Migraine without aura ( 23793025 27322543) Multisite chronic pain ( 33830993 31194737) Nonunion in individuals with fractures ( 30680360) Obesity-related traits ( 23251661) Osteoarthritis (hip) ( 30664745 30374069) Peak expiratory flow ( 30804560) PR interval ( 32439900) Pulmonary function (smoking interaction) ( 23284291) Response to antipsychotic treatment ( 20195266) Shoulder impingement or rotator cuff tear ( 33482370) Subiculum volume ( 30279459) Survival in pancreatic cancer ( 28470677) Total hippocampal volume ( 30279459) Transverse temporal cortex volume ( 31530798) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		4 interacting genes: CHRM5 POLE3 TNC TRIM32
Entrez ID		23245
HPRD ID		12498
Ensembl ID		ENSG00000148219
Uniprot IDs		B3KN99 B7ZKP4 B7ZKP5 O75129 X6R5P2
PDB IDs		5J67 5J68 5J69
Enriched GO Terms of Interacting Partners?
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