KDM4C

Description		lysine demethylase 4C
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Zinc Ion Binding Enzyme Binding Histone Demethylase Activity Histone H3-methyl-lysine-9 Demethylase Activity Androgen Receptor Binding Histone H3-methyl-lysine-36 Demethylase Activity
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Histone H3-K9 Demethylation Positive Regulation Of Neuron Differentiation Regulation Of Androgen Receptor Signaling Pathway Histone H3-K36 Demethylation
Pathways		HDMs demethylate histones Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) Artificially sweetened beverage consumption ( 31046077) Body mass index ( 25673413) Body size at age 10 ( 32376654) Caffeine consumption from tea ( 33287642) California verbal learning test score ( 31596458) HIV-1 susceptibility ( 25786224) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Radiation response ( 20923822) Response to fenofibrate (adiponectin levels) ( 23149075) Schizophrenia ( 30285260) Serum metabolite levels ( 31636271 33031748) Serum metabolite levels (CMS) ( 31636271) Systemic lupus erythematosus ( 26606652)
Interacting Genes		2 interacting genes: H3C1 H3C14
Entrez ID		23081
HPRD ID		12016
Ensembl ID		ENSG00000107077
Uniprot IDs		B0QZ60 Q9H3R0
PDB IDs		2XDP 2XML 4XDO 4XDP 5FJH 5FJK 5KR7
Enriched GO Terms of Interacting Partners?
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