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WAPL

Description WAPL cohesin release factor
Image
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Chromatin
  • Synaptonemal Complex
  • Nucleus
  • Nucleoplasm
  • Chromosome
  • Cytoplasm
  • Golgi Apparatus
  • Centrosome
  • Cytosol
  • Intercellular Bridge
  • Mitotic Spindle
Molecular Function
  • Protein Binding
Biological Process
  • Mitotic Cell Cycle
  • Negative Regulation Of DNA Replication
  • Response To Toxic Substance
  • Negative Regulation Of Chromatin Binding
  • Negative Regulation Of Sister Chromatid Cohesion
  • Positive Regulation Of Fibroblast Proliferation
  • Cell Division
  • Regulation Of Chromosome Segregation
  • Regulation Of Chromosome Condensation
  • Protein Localization To Chromatin
  • Regulation Of Cohesin Loading
Pathways
  • Separation of Sister Chromatids
  • Establishment of Sister Chromatid Cohesion
  • Cohesin Loading onto Chromatin
  • Resolution of Sister Chromatid Cohesion
Drugs
Diseases
GWAS
  • Parental longevity (father's age at death) ( 31484785)
Interacting Genes 5 interacting genes: ARAP1 MTNR1A RAD21 SUMO2 XRN1
Entrez ID 23063
HPRD ID 11072
Ensembl ID ENSG00000062650
Uniprot IDs A8K273 B2RTX8 Q7Z5K2
PDB IDs 4K6J 5HDT
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025