PLA2R1

Description		phospholipase A2 receptor 1
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Cell Surface Integral Component Of Membrane Receptor Complex
	Molecular Function	Carbohydrate Binding Signaling Receptor Activity Phospholipase Binding
	Biological Process	Positive Regulation Of Cytokine Production Receptor-mediated Endocytosis Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Reactive Oxygen Species Metabolic Process Positive Regulation Of Arachidonic Acid Secretion Replicative Senescence Oxidative Stress-induced Premature Senescence Negative Regulation Of Phospholipase A2 Activity Negative Regulation Of Arachidonic Acid Secretion Positive Regulation Of Glomerular Visceral Epithelial Cell Apoptotic Process
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		Bilirubin levels ( 20639394) Blood protein levels ( 30072576 29875488) Crohn's disease ( 26192919) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 26192919) Membranous nephropathy ( 32231244 27333618) Platelet count ( 32888494) Plateletcrit ( 32888494) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Refractive error ( 32231278) Tourette syndrome ( 30818990) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: PLA2G10 PLA2G2A SCN2A
Entrez ID		22925
HPRD ID		09222
Ensembl ID		ENSG00000153246
Uniprot IDs		B7ZML4 Q13018
PDB IDs		6JLI
Enriched GO Terms of Interacting Partners?
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