SKA1

Description		spindle and kinetochore associated complex subunit 1
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GO Annotations	Cellular Component	Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Binding Microtubule Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
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Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)
Interacting Genes		12 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SNAPIN SPC24 SSC5D SYCE1
Entrez ID		220134
HPRD ID		12689
Ensembl ID		ENSG00000154839
Uniprot IDs		A0A024R294 Q96BD8
PDB IDs		4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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