EYA4

Description		EYA transcriptional coactivator and phosphatase 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	DNA Repair Visual Perception Sensory Perception Of Sound Anatomical Structure Morphogenesis Histone Dephosphorylation Cell Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of DNA Repair Inner Ear Development Anatomical Structure Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Asthma with severe exacerbations ( 32841424) Atrial fibrillation ( 29892015) Bone mineral density (paediatric, skull) ( 24945404) Chronic pain ( 33685280) Estimated glomerular filtration rate ( 31152163 31015462) Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Glomerular filtration rate (creatinine) ( 28452372) Heel bone mineral density ( 30598549 28869591) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196 34021172) Hip index ( 34021172) Methadone dose in opioid dependence ( 28115739) Neutrophil count ( 32888494) Protein quantitative trait loci ( 18464913) Response to angiotensin II receptor blocker therapy ( 22566498) Triglyceride levels ( 32203549 32154731) Visceral fat ( 22589738) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: AATK ERBB3 SIX1
Entrez ID		2070
HPRD ID		04648
Ensembl ID		ENSG00000112319
Uniprot IDs		A0A0S2Z3Q2 A0A0S2Z3V9 B4DIV6 B4DRQ6 F2Z2Y1 O95677 Q96CJ7
PDB IDs
Enriched GO Terms of Interacting Partners?
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