EEF2

Description		eukaryotic translation elongation factor 2
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GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Aggresome Secretory Granule Lumen Polysomal Ribosome Membrane Raft Synapse Extracellular Exosome Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex
	Molecular Function	P53 Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding 5S RRNA Binding Protein Kinase Binding Ribosome Binding Cadherin Binding Actin Filament Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Response To Ischemia Skeletal Muscle Contraction Translational Elongation Aging Response To Xenobiotic Stimulus Glial Cell Proliferation Response To Estradiol Response To Endoplasmic Reticulum Stress Skeletal Muscle Cell Differentiation Response To Hydrogen Peroxide Response To Ethanol Positive Regulation Of Translation Response To Folic Acid Cellular Response To Brain-derived Neurotrophic Factor Stimulus Positive Regulation Of Cytoplasmic Translation
Pathways		Peptide chain elongation Peptide chain elongation Uptake and function of diphtheria toxin Synthesis of diphthamide-EEF2 Synthesis of diphthamide-EEF2 Neutrophil degranulation Protein methylation
Drugs		Adenosine-5-Diphosphoribose Diphthamide Guanosine-5'-Diphosphate N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE Esketamine Moxetumomab Pasudotox
Diseases
GWAS
Interacting Genes		22 interacting genes: CCT2 CDKN2A CREBBP DISC1 DUX4 EEF2K EP300 ESR1 HNRNPD LINC01554 MAPKAPK3 MLH1 NDRG1 PPM1A PPP2CA PPP2R1A PPP2R1B PTEN SUMO2 TP53 TRPM7 UCHL5
Entrez ID		1938
HPRD ID		00561
Ensembl ID		ENSG00000167658
Uniprot IDs		A0A384N6H1 P13639
PDB IDs		4V6X 6D9J 6Z6M 6Z6N
Enriched GO Terms of Interacting Partners?
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