GLIS3

Description		GLIS family zinc finger 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23562540) Anxiety ( 33859377) Blood sugar levels ( 29403010) Brain morphology (MOSTest) ( 32665545) Central corneal thickness ( 32528159 29760442) Cerebrospinal P-tau181p levels ( 28247064) Cerebrospinal T-tau levels ( 28247064) Chin dimples ( 27182965) Chronic obstructive pulmonary disease ( 30804561) Circulating leptin levels or type 2 diabetes ( 32341051) Fasting blood glucose ( 33842983 25631608 20081858 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting glucose ( 33402679 34059833) Fasting insulin ( 34059833) Fasting plasma glucose ( 25187374) FEV1 ( 30804560) Free thyroxine concentration ( 30367059) Glaucoma (primary angle closure) ( 27064256) Height ( 28552196) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Homeostasis model assessment of beta-cell function ( 20081858) Intraocular pressure ( 29617998 29785010 30054594 30591961 29235454) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low hand grip strength (60 years and older) (FNIH) ( 33510174) Low high density lipoprotein cholesterol levels ( 26879886) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Medication use (adrenergics, inhalants) ( 31015401) Metabolite levels ( 23823483) Methotrexate phramacokinetics (acute lymphoblastic leukemia) ( 19901119) Monocyte count ( 32888494) Neurociticism ( 29500382) NHDL cholesterol levels ( 32902719) Nicotine dependence ( 28440896) Offspring birth weight ( 31043758) Osteoarthritis of the hip or knee ( 29436472) Osteoarthritis of the hip or knee (with total joint replacement) ( 29436472) Peak expiratory flow ( 30804560) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Platelet count ( 32888494) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy) ( 24554482) Spontaneous preterm birth (preterm delivery) ( 25599974) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997) Total cholesterol levels ( 32902719) Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Type 1 diabetes ( 25751624 19430480 33830302 18840781) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 22961080 32499647 22158537 30718926 28869590) Vaginal microbiome composition (community state type) ( 32723796) White blood cell count ( 32888494)
Interacting Genes		11 interacting genes: BAG3 CIB1 CLNK ENO1 ITCH KRTAP6-1 NEK6 SUFU TRAF1 TRIB3 TRIP6
Entrez ID		169792
HPRD ID		13582
Ensembl ID		ENSG00000107249
Uniprot IDs		A0A0S2Z689 Q1PHJ8 Q8NEA6
PDB IDs
Enriched GO Terms of Interacting Partners?
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