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CCN2
Description
cellular communication network factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cis-Golgi Network
Cytosol
Plasma Membrane
Cell Cortex
Extracellular Matrix
Perinuclear Region Of Cytoplasm
Collagen-containing Extracellular Matrix
Molecular Function
Fibronectin Binding
Integrin Binding
Protein Binding
Insulin-like Growth Factor Binding
Protein C-terminus Binding
Growth Factor Activity
Heparin Binding
Biological Process
Cartilage Condensation
Ossification
Angiogenesis
Tissue Homeostasis
Positive Regulation Of Protein Phosphorylation
Cell Adhesion
Cell-matrix Adhesion
Signal Transduction
Integrin-mediated Signaling Pathway
Aging
Positive Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Epidermis Development
Response To Wounding
Response To Glucose
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cell Death
Cell Migration
Cell Differentiation
Lung Development
Regulation Of Chondrocyte Differentiation
Response To Estradiol
Positive Regulation Of Collagen Biosynthetic Process
Response To Anoxia
Intracellular Signal Transduction
Chondrocyte Proliferation
Response To Amino Acid
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Peptide Hormone
Positive Regulation Of Cell Differentiation
Positive Regulation Of JNK Cascade
Positive Regulation Of Cell Activation
Response To Mineralocorticoid
Positive Regulation Of Stress Fiber Assembly
Cytosolic Calcium Ion Transport
Positive Regulation Of Cardiac Muscle Contraction
Negative Regulation Of Cell Death
Extracellular Matrix Constituent Secretion
Positive Regulation Of G0 To G1 Transition
Positive Regulation Of ERK1 And ERK2 Cascade
Response To Fatty Acid
DNA Biosynthetic Process
Reactive Oxygen Species Metabolic Process
Pathways
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS
Interacting Genes
13 interacting genes:
ACTB
AP3D1
CCN3
ERBB4
FBLN1
HSPG2
LIMS1
LRP1
MTDH
TGFB1
TGFB2
TGFB3
VEGFA
Entrez ID
1490
HPRD ID
00412
Ensembl ID
ENSG00000118523
Uniprot IDs
P29279
Q5M8T4
PDB IDs
Enriched GO Terms of Interacting Partners
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