FCHO2

Description		FCH and mu domain containing endocytic adaptor 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle Presynaptic Endocytic Zone Membrane
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Membrane Invagination Clathrin Coat Assembly Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis Protein Localization To Plasma Membrane
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
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Diseases
GWAS		Albumin-globulin ratio ( 29403010) Aspartate aminotransferase levels ( 33547301 29403010 33339817) Discordance in emotional problems in monozygotic twins ( 27043157) Eyebrow thickness ( 26926045) Factor VIII levels ( 30586737) Heel bone mineral density ( 30598549) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin concentration ( 32888494) Mean platelet volume ( 32888494) Monobrow thickness ( 26926045) Non-albumin protein levels ( 29403010) Red cell distribution width ( 32888494 27863252) Serum albumin level ( 29403010) Small cell lung carcinoma ( 28604730) vWF levels ( 30586737) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes		7 interacting genes: DAB2 EPS15 EPS15L1 ITSN1 MRPS27 RHOU UBC
Entrez ID		115548
HPRD ID		13319
Ensembl ID		ENSG00000157107
Uniprot IDs		Q0JRZ9
PDB IDs		2V0O
Enriched GO Terms of Interacting Partners?
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