KLF12

Description		Kruppel like factor 12
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Aspartate aminotransferase levels ( 33547301) Asthma ( 34103634 32296059) Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Bronchopulmonary dysplasia ( 23897914) Cervical high-risk human papilloma virus infection ( 33225922) Colorectal cancer ( 30529582) Craniofacial microsomia ( 26853712) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Endometrial cancer ( 30093612 27135401) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Energy expenditure ( 30071075) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494 27863252) Glucocorticoid-induced osteonecrosis ( 26265699) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549 28869591) Heschl's gyrus morphology ( 25130324) Lean body mass ( 28724990) Liver enzyme levels (alkaline phosphatase) ( 33972514) Long QT syndrome ( 32429735) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean platelet volume ( 32888494) Menarche (age at onset) ( 25231870) Neurofibrillary tangles ( 25188341) Neutrophil percentage of white cells ( 32888494) Pancreatic cancer ( 29422604 20101243 26098869 25086665) Phospholipid levels (plasma) ( 22359512) Photic sneeze reflex ( 27182965) QRS duration ( 30679814 27577874 30012220 21076409 27659466) QT interval ( 24952745 29874175) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Systemic lupus erythematosus ( 19838195) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Triglyceride levels ( 32203549) Type 2 diabetes ( 25760438) Waist-to-hip ratio adjusted for body mass index ( 27195708) White blood cell count ( 32888494)
Interacting Genes		7 interacting genes: APP CTBP1 DNMT3L EHMT2 FHL2 FHL3 THAP1
Entrez ID		11278
HPRD ID		06336
Ensembl ID		ENSG00000118922
Uniprot IDs		Q8WWI3 Q9Y4X4
PDB IDs
Enriched GO Terms of Interacting Partners?
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