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SEC61B

Description SEC61 translocon subunit beta
Image
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Sec61 Translocon Complex
  • Endoplasmic Reticulum Membrane
  • Cytosol
  • Membrane
  • Integral Component Of Membrane
  • Endoplasmic Reticulum Sec Complex
  • Endoplasmic Reticulum Quality Control Compartment
Molecular Function
  • RNA Binding
  • Protein Binding
  • Ribosome Binding
  • Epidermal Growth Factor Binding
Biological Process
  • SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation
  • Ubiquitin-dependent ERAD Pathway
  • Retrograde Protein Transport, ER To Cytosol
  • Posttranslational Protein Targeting To Membrane, Translocation
Pathways
  • ER-Phagosome pathway
  • SRP-dependent cotranslational protein targeting to membrane
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Asthma ( 31959851)
  • Callous-unemotional behaviour ( 23874384)
  • Gestational age at birth (maternal effect) ( 28877031)
  • HDL cholesterol levels ( 32203549)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Triglyceride levels ( 32203549)
Interacting Genes 19 interacting genes: APOB ARL6 ATP13A2 AURKA BAG6 BMPR1A BUB1 CDKN2A FBXW7 GET3 GET4 MCC MLH3 MORC3 MUTYH SEC63 SERP1 SPC25 TRAM1
Entrez ID 10952
HPRD ID 06715
Ensembl ID ENSG00000106803
Uniprot IDs P60468
PDB IDs 6W6L
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025