NFAT5

Description		nuclear factor of activated T cells 5
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cytokine Production Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Response To Osmotic Stress Signal Transduction Excretion Positive Regulation Of Gene Expression Calcineurin-NFAT Signaling Cascade Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Cytokine Stimulus Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood osmolality (transformed sodium) ( 28360221) Blood urea nitrogen levels ( 31152163 29403010) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Chloride levels ( 29403010) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Estimated glomerular filtration rate ( 31015462 30604766) Hand grip strength ( 29691431) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Hyperuricemia ( 29124443) Intralaminar thalamic nuclei volume ( 34006833) Menarche (age at onset) ( 27182965 21102462 25231870) Metabolic syndrome ( 31589552) Pulse pressure ( 28135244 27841878) Self-reported risk-taking behaviour ( 30181555) Serum uric acid levels ( 30993211 29124443) SjÃ¶gren's syndrome ( 28076899) Smoking initiation (ever regular vs never regular) ( 30679032) Sodium levels ( 29403010) Triglyceride levels ( 32154731) Type 2 diabetes ( 30054458 30297969) Urate levels ( 31985003 23263486)
Interacting Genes		5 interacting genes: FOXP3 NFE2L2 NUTF2 TBC1D4 TRIM14
Entrez ID		10725
HPRD ID		05272
Ensembl ID		ENSG00000102908
Uniprot IDs		A0A024R734 O94916
PDB IDs		1IMH
Enriched GO Terms of Interacting Partners?
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