ABCB6

Description		ATP binding cassette subfamily B member 6 (Langereis blood group)
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Lysosomal Membrane Endosome Vacuolar Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Integral Component Of Membrane Integral Component Of Mitochondrial Outer Membrane Early Endosome Membrane Multivesicular Body Membrane Melanosome Membrane Endolysosome Membrane ATP-binding Cassette (ABC) Transporter Complex Extracellular Exosome
	Molecular Function	ATP Binding ABC-type Heme Transporter Activity Efflux Transmembrane Transporter Activity ATP Hydrolysis Activity Heme Binding ATPase-coupled Transmembrane Transporter Activity Tetrapyrrole Binding ABC-type Transporter Activity
	Biological Process	Porphyrin-containing Compound Metabolic Process Porphyrin-containing Compound Biosynthetic Process Heme B Biosynthetic Process Cellular Copper Ion Homeostasis Cellular Iron Ion Homeostasis Brain Development Heme Transport Tetrapyrrole Metabolic Process Heme Transmembrane Transport Heme Metabolic Process Skin Development Transmembrane Transport Cellular Detoxification Of Cadmium Ion Melanosome Assembly
Pathways		Mitochondrial ABC transporters Defective ABCB6 causes MCOPCB7
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		1 interacting genes: PIK3R3
Entrez ID		10058
HPRD ID		09261
Ensembl ID		ENSG00000115657
Uniprot IDs		Q9NP58
PDB IDs		3NH6 3NH9 3NHA 3NHB 7D7N 7D7R
Enriched GO Terms of Interacting Partners?
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