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Search Results for: Respiratory

2697 interactions found:

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Pathways 2
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Diseases 2
UCP3 and YWHAZ uncoupling protein 3 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  • The fatty acid cycling model
  • The proton buffering model
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Deactivation of the beta-catenin transactivating complex
  • Rap1 signalling
  • GP1b-IX-V activation signalling
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Interleukin-3, Interleukin-5 and GM-CSF signaling
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • NOTCH4 Activation and Transmission of Signal to the Nucleus
  • Negative regulation of NOTCH4 signaling
  • Regulation of localization of FOXO transcription factors
  • Phenethyl Isothiocyanate
UQCRC1 and RTN4 ubiquinol-cytochrome c reductase core protein 1 reticulon 4
  • Respiratory electron transport
  • Axonal growth inhibition (RHOA activation)
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • Myxothiazol
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
UQCRC1 and TRIM63 ubiquinol-cytochrome c reductase core protein 1 tripartite motif containing 63
  • Respiratory electron transport
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • Antigen processing: Ubiquitination & Proteasome degradation
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • Myxothiazol
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
UQCRC2 and RTN4 ubiquinol-cytochrome c reductase core protein 2 reticulon 4
  • Respiratory electron transport
  • Axonal growth inhibition (RHOA activation)
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
UQCRH and ARL8A ubiquinol-cytochrome c reductase hinge protein ADP ribosylation factor like GTPase 8A
  • Respiratory electron transport
  • Neutrophil degranulation
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
UQCRH and FAM189B ubiquinol-cytochrome c reductase hinge protein family with sequence similarity 189 member B
  • Respiratory electron transport
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
UQCRH and RNF24 ubiquinol-cytochrome c reductase hinge protein ring finger protein 24
  • Respiratory electron transport
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
VDAC2 and CYCS voltage dependent anion channel 2 cytochrome c, somatic
  • Ub-specific processing proteases
  • Mitochondrial calcium ion transport
  • Release of apoptotic factors from the mitochondria
  • Formation of apoptosome
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • Transcriptional activation of mitochondrial biogenesis
  • Detoxification of Reactive Oxygen Species
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Regulation of the apoptosome activity
  • Regulation of the apoptosome activity
  • Aluminium monostearate
  • PRLX 93936
  • Minocycline
  • Protoporphyrin Ix Containing Co
  • Heme C
  • Imidazole
  • Protoporphyrin Ix Containing Zn
  • N-Trimethyllysine
  • Zinc Substituted Heme C
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
WNT2 and UQCR11 Wnt family member 2 ubiquinol-cytochrome c reductase, complex III subunit XI
  • WNT ligand biogenesis and trafficking
  • WNT ligand biogenesis and trafficking
  • Class B/2 (Secretin family receptors)
  • Respiratory electron transport
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
BAG6 and NDUFB11 BAG cochaperone 6 NADH:ubiquinone oxidoreductase subunit B11
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Respiratory electron transport
  • Complex I biogenesis
EPM2A and COX5A EPM2A glucan phosphatase, laforin cytochrome c oxidase subunit 5A
  • Glycogen synthesis
  • Myoclonic epilepsy of Lafora
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cholic Acid
  • N-Formylmethionine
  • Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
NDUFA12 and ZNF768 NADH:ubiquinone oxidoreductase subunit A12 zinc finger protein 768
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
H1-10 and ACAD9 H1.10 linker histone acyl-CoA dehydrogenase family member 9
  • Complex I biogenesis
  • Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
COX5A and KRT40 cytochrome c oxidase subunit 5A keratin 40
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Keratinization
  • Formation of the cornified envelope
  • Cholic Acid
  • N-Formylmethionine
COX5A and EXOSC8 cytochrome c oxidase subunit 5A exosome component 8
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Cholic Acid
  • N-Formylmethionine
COX5A and COPS6 cytochrome c oxidase subunit 5A COP9 signalosome subunit 6
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
  • Cholic Acid
  • N-Formylmethionine
RNF7 and CYCS ring finger protein 7 cytochrome c, somatic
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Release of apoptotic factors from the mitochondria
  • Formation of apoptosome
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • Transcriptional activation of mitochondrial biogenesis
  • Detoxification of Reactive Oxygen Species
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Regulation of the apoptosome activity
  • Regulation of the apoptosome activity
  • Minocycline
  • Protoporphyrin Ix Containing Co
  • Heme C
  • Imidazole
  • Protoporphyrin Ix Containing Zn
  • N-Trimethyllysine
  • Zinc Substituted Heme C
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
TRAF4 and NCF1 TNF receptor associated factor 4 neutrophil cytosolic factor 1
  • ROS and RNS production in phagocytes
  • Cross-presentation of particulate exogenous antigens (phagosomes)
  • Detoxification of Reactive Oxygen Species
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases Activate NADPH Oxidases
  • Dextromethorphan
  • Chronic granulomatous disease, including the following four diseases: X-linked CGD (gp91 phox CGD); p22phox deficiency (p22phox CGD); p47phox deficiency (p47phox CGD); p67phox deficiency (p67phox CGD)
LRPPRC and PPARGC1A leucine rich pentatricopeptide repeat containing PPARG coactivator 1 alpha
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • PPARA activates gene expression
  • Transcriptional activation of mitochondrial biogenesis
  • Activation of PPARGC1A (PGC-1alpha) by phosphorylation
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • SUMOylation of transcription cofactors
  • Circadian Clock
  • Circadian Clock
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX2 expression and activity
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
MYBBP1A and PPARGC1A MYB binding protein 1a PPARG coactivator 1 alpha
  • B-WICH complex positively regulates rRNA expression
  • PPARA activates gene expression
  • Transcriptional activation of mitochondrial biogenesis
  • Activation of PPARGC1A (PGC-1alpha) by phosphorylation
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • SUMOylation of transcription cofactors
  • Circadian Clock
  • Circadian Clock
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX2 expression and activity
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes

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