Wiki-CORONA

Search Results for: Respiratory

2697 interactions found:

Sort by: Relevance Number of Pathways Number of Drugs Number of Diseases
Symbols Name 1 Name 2
Pathways 1
Pathways 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
KRAS and UQCRC1 KRAS proto-oncogene, GTPase ubiquinol-cytochrome c reductase core protein 1
  • Signaling by moderate kinase activity BRAF mutants
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • RUNX3 regulates p14-ARF
  • RAS GTPase cycle mutants
  • Signaling downstream of RAS mutants
  • Respiratory electron transport
  • [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
  • FARNESYL DIPHOSPHATE
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • Myxothiazol
  • 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
  • METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • FAMOXADONE
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
  • UBIQUINONE-2
  • Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
  • Pancreatic cancer
  • Gastric cancer
  • Colorectal cancer
  • Non-small cell lung cancer
  • Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
  • Oral cancer
  • Acute myeloid leukemia (AML)
  • Endometrial Cancer
  • Multiple myeloma
  • Squamous cell carcinoma
  • Kaposi's sarcoma
  • Cholangiocarcinoma
  • Thyroid cancer
  • Cervical cancer
  • Hepatocellular carcinoma
  • Ovarian cancer
  • Gallbladder cancer
KRAS and NDUFA13 KRAS proto-oncogene, GTPase NADH:ubiquinone oxidoreductase subunit A13
  • Signaling by moderate kinase activity BRAF mutants
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • RUNX3 regulates p14-ARF
  • RAS GTPase cycle mutants
  • Signaling downstream of RAS mutants
  • Respiratory electron transport
  • Complex I biogenesis
  • [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
  • FARNESYL DIPHOSPHATE
  • NADH
  • Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
  • Pancreatic cancer
  • Gastric cancer
  • Colorectal cancer
  • Non-small cell lung cancer
  • Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
  • Oral cancer
  • Acute myeloid leukemia (AML)
  • Endometrial Cancer
  • Multiple myeloma
  • Squamous cell carcinoma
  • Kaposi's sarcoma
  • Cholangiocarcinoma
  • Thyroid cancer
  • Cervical cancer
  • Hepatocellular carcinoma
  • Ovarian cancer
  • Gallbladder cancer
KRT31 and COX5A keratin 31 cytochrome c oxidase subunit 5A
  • Keratinization
  • Formation of the cornified envelope
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cholic Acid
  • N-Formylmethionine
KRT31 and COA5 keratin 31 cytochrome c oxidase assembly factor 5
  • Keratinization
  • Formation of the cornified envelope
LIG4 and NDUFB10 DNA ligase 4 NADH:ubiquinone oxidoreductase subunit B10
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
LIG4 and NDUFA13 DNA ligase 4 NADH:ubiquinone oxidoreductase subunit A13
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
LIG4 and MT-CO1 DNA ligase 4 cytochrome c oxidase subunit I
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cholic Acid
  • N-Formylmethionine
  • Oxygen
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
  • Leber optic atrophy; Leber hereditary optic atrophy (LHON)
LIG4 and MT-CO2 DNA ligase 4 cytochrome c oxidase subunit II
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cholic Acid
  • N-Formylmethionine
  • Talmapimod
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
LIG4 and MT-CO3 DNA ligase 4 cytochrome c oxidase III
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cholic Acid
  • N-Formylmethionine
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
  • Leber optic atrophy; Leber hereditary optic atrophy (LHON)
LIG4 and MT-ND1 DNA ligase 4 NADH dehydrogenase, subunit 1 (complex I)
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
  • Methoxyflurane
  • Halothane
  • Desflurane
  • Sevoflurane
  • N-Formylmethionine
  • Phenethyl Isothiocyanate
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
  • Leber optic atrophy; Leber hereditary optic atrophy (LHON)
LIG4 and MT-ND4 DNA ligase 4 NADH dehydrogenase, subunit 4 (complex I)
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
  • Leber optic atrophy; Leber hereditary optic atrophy (LHON)
LIG4 and MT-ND5 DNA ligase 4 NADH dehydrogenase, subunit 5 (complex I)
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
  • Iodine
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
  • Leber optic atrophy; Leber hereditary optic atrophy (LHON)
LMNA and SELENOK lamin A/C selenoprotein K
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
LMNA and CYBC1 lamin A/C cytochrome b-245 chaperone 1
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
MAGEA11 and NDUFB9 MAGE family member A11 NADH:ubiquinone oxidoreductase subunit B9
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
MAGEA11 and COX7A2L MAGE family member A11 cytochrome c oxidase subunit 7A2 like
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
MAK and NDUFB7 male germ cell associated kinase NADH:ubiquinone oxidoreductase subunit B7
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
MDFI and NDUFA7 MyoD family inhibitor NADH:ubiquinone oxidoreductase subunit A7
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH
MDM2 and SDHC MDM2 proto-oncogene succinate dehydrogenase complex subunit C
  • AKT phosphorylates targets in the cytosol
  • Oxidative Stress Induced Senescence
  • Oncogene Induced Senescence
  • SUMOylation of transcription factors
  • SUMOylation of ubiquitinylation proteins
  • Trafficking of AMPA receptors
  • Constitutive Signaling by AKT1 E17K in Cancer
  • Ub-specific processing proteases
  • Regulation of TP53 Activity through Phosphorylation
  • Regulation of TP53 Degradation
  • Regulation of TP53 Activity through Methylation
  • Stabilization of p53
  • Regulation of RUNX3 expression and activity
  • Respiratory electron transport
  • Citric acid cycle (TCA cycle)
  • Zinc
  • Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone
  • Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone
  • Succinic acid
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • UBIQUINONE-1
  • Choriocarcinoma
  • Osteosarcoma
  • Glioma
  • Penile cancer
  • Alveolar rhabdomyosarcoma
MEF2A and NDUFB9 myocyte enhancer factor 2A NADH:ubiquinone oxidoreductase subunit B9
  • ERK/MAPK targets
  • Myogenesis
  • Respiratory electron transport
  • Complex I biogenesis
  • NADH

Page 10 out of 135 pages