LPXN and PLEKHN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LPXN	PLEKHN1
Description		leupaxin	pleckstrin homology domain containing N1
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm	Mitochondrion Cytoskeleton Plasma Membrane Mitochondrial Membrane
	Molecular Function	Transcription Coregulator Activity Protein Binding Metal Ion Binding	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly Regulation Of Nucleic Acid-templated Transcription	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)	Height ( 31562340) Parkinson's disease ( 26227905)
Interacting Genes		27 interacting genes: GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RUNX1T1 SFI1 TXLNB VCL ZNF175 ZNF426	11 interacting genes: CBY2 LPXN LZTS2 PUSL1 REL RFX6 TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27
Entrez ID		9404	84069
HPRD ID		05651	13190
Ensembl ID		ENSG00000110031	ENSG00000187583
Uniprot IDs		B7Z5P7 O60711	Q494U1
PDB IDs		1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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