HECW2 and TP73

  • Number of citations of the paper that reports this interaction (PubMedID 12890487)
  • 27
  • Data Source:
  • HPRD (in vitro, in vivo)

HECW2

TP73

Description HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 tumor protein p73
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Heel bone mineral density ( 30598549)
  • Hip circumference adjusted for BMI ( 28552196)
  • Response to fenofibrate (LDL cholesterol levels) ( 27002377)
  • Joint damage in rheumatoid arthritis ( 31596875)
  • Visceral adipose tissue adjusted for BMI ( 22589738)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Visceral fat ( 22589738)
  • Waist-hip ratio ( 28552196)
Interacting Genes 8 interacting genes: CBX1 CBX3 CBX5 FZR1 TP73 UBE2D2 UBE2D3 UBE2L3 64 interacting genes: ABL1 ATF3 AURKA BIN1 BUB1B CABLES1 CCNB1 CCND1 CCNE1 CDK1 CDK2 CEBPZ CHD3 CREBBP CSNK2A1 DAXX DDB1 EP300 FBXO45 FLNA HCK HECW2 HIPK2 HIPK3 HMGB1 HRAS IKBKB ITCH KAT2B MAPK8 MDM2 MDM4 MUL1 MYC NEDD4 NFYB PFDN5 PIAS1 PIN1 PLK1 PML PPP1R13B PRKACB RACK1 RANBP9 RCHY1 RPL11 RPL5 SIRT1 SMAD2 SMAD3 SP1 SP3 SUMO1 TP53 TP63 TRIM28 UBE2D3 UBE2I WT1 WWOX WWP2 XPO1 YAP1
Entrez ID 57520 7161
HPRD ID 17099 03587
Ensembl ID ENSG00000138411 ENSG00000078900
Uniprot IDs A0A2R8Y6F3 Q9P2P5 A0A0C4DFW9 A1PQX5 O15350
PDB IDs 2LFE 1COK 1DXS 2KBY 2MPS 2NB1 2WQI 2WQJ 2WTT 2XWC 3VD0 3VD1 3VD2 4A63 4G82 4G83 4GUO 4GUQ 5HOB 5HOC 5KBD 6FGS 6IJQ
Enriched GO Terms of Interacting Partners?
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