HUWE1 and HDAC2

  • Number of citations of the paper that reports this interaction (PubMedID 22016339)
  • 25
  • Data Source:
  • BioGRID (enzymatic study)

HUWE1

HDAC2

Description HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 histone deacetylase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308)
  • Metabolite levels ( 23823483)
Interacting Genes 35 interacting genes: ABL1 ATOH1 CALM1 CCL1 CDKN2A CTNNB1 CUL4B ERG H2AX HDAC2 HSPB1 LAPTM5 MCL1 MYCN PCNA PIAS2 POLB POLL PPP5C RBBP7 RNF11 SMAD2 SMAD9 TBP TNS2 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2L3 USP4 USP7 WBP2 106 interacting genes: ANTXR1 APPL1 ARID4A AURKA BCL11A BRCA1 BRMS1 BRMS1L BUB3 CABIN1 CDC20 CDH1 CDKN1A CDYL CHD3 CHFR CIR1 CSNK2A1 CSNK2A2 CTBP1 CYTOR DAXX DDX20 DMAP1 DNMT1 DNMT3B EED EID2 FKBP3 FOXO3 FTCD FYN GATA3 H2AC1 H2AC20 H2BC21 H3-4 H3C1 HDAC1 HDAC10 HDAC7 HIF1A HIF1AN HOPX HUWE1 IFRD1 IKZF1 IKZF4 ING1 LAMA4 MAD1L1 MBD2 MBD3L2 MEN1 MTA1 MTA2 MXD1 NACC2 NRIP1 PA2G4 PADI4 PHB2 PHF21A PIAS4 PML PPARD PPP1R8 PTMA RBBP4 RBBP7 RBP1 RCOR1 RELA REV3L RFX5 RUNX3 SALL1 SAP30 SETDB1 SIN3A SMAD2 SMARCA5 SMYD1 SNW1 SP1 SP3 SPEN SS18L1 STAT3 STK25 SUMO2 SUV39H1 SYK TFCP2 THRA THRB TNS4 TOP2A TOP2B TP53 TREML2 USP4 VHL YY1 ZBTB16 ZNF461
Entrez ID 10075 3066
HPRD ID 06608 05521
Ensembl ID ENSG00000086758 ENSG00000196591
Uniprot IDs A0A024R9W5 Q7Z6Z7 Q92769
PDB IDs 2EKK 2MUL 3G1N 3H1D 5C6H 5LP8 6FYH 6MIW 6PFL 3MAX 4LXZ 4LY1 5IWG 5IX0 6G3O
Enriched GO Terms of Interacting Partners?
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