NRG2

Description		neuregulin 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Growth Factor Activity
	Biological Process	MAPK Cascade Signal Transduction Nervous System Development Intracellular Signal Transduction ERBB2 Signaling Pathway Animal Organ Development Positive Regulation Of Protein Kinase B Signaling Regulation Of Cell Motility
Pathways		Signaling by ERBB2 Signaling by ERBB4 Signaling by ERBB4 SHC1 events in ERBB2 signaling SHC1 events in ERBB2 signaling PI3K events in ERBB4 signaling SHC1 events in ERBB4 signaling Nuclear signaling by ERBB4 PIP3 activates AKT signaling GRB7 events in ERBB2 signaling Downregulation of ERBB2:ERBB3 signaling GRB2 events in ERBB2 signaling PI3K events in ERBB2 signaling Constitutive Signaling by Aberrant PI3K in Cancer RAF/MAP kinase cascade ERBB2 Regulates Cell Motility PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling ERBB2 Activates PTK6 Signaling Downregulation of ERBB2 signaling Signaling by ERBB2 KD Mutants Signaling by ERBB2 TMD/JMD mutants
Drugs
Diseases
GWAS		Body mass index ( 26426971) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980)
Interacting Genes		3 interacting genes: ERBB3 ERBB4 FBN2
Entrez ID		9542
HPRD ID		04821
Ensembl ID		ENSG00000158458
Uniprot IDs		F5GZS7 O14511
PDB IDs
Enriched GO Terms of Interacting Partners?
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