CD33

Description		CD33 molecule
Image
GO Annotations	Cellular Component	Nucleoplasm Peroxisome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Specific Granule Membrane Tertiary Granule Membrane
	Molecular Function	Protein Binding Protein Phosphatase Binding Carbohydrate Binding Sialic Acid Binding Signaling Receptor Activity
	Biological Process	Immune Response-inhibiting Signal Transduction Cell Adhesion Signal Transduction Cell-cell Signaling Negative Regulation Of Cell Proliferation Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Neutrophil Degranulation Positive Regulation Of Protein Secretion Regulation Of Immune Response Negative Regulation Of Calcium Ion Transport Cell-cell Adhesion Positive Regulation Of Protein Tyrosine Phosphatase Activity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs		Gemtuzumab ozogamicin
Diseases
GWAS		Alzheimer's disease ( 18976728 31473137) Alzheimer's disease (late onset) ( 21460841 30617256 24162737 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Blood protein levels ( 30072576 29875488 28240269) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) HIV-1 susceptibility ( 25786224) Platelet count ( 27863252) Plateletcrit ( 27863252) Triacylglyceride levels ( 31551469) White blood cell count ( 27863252)
Interacting Genes		6 interacting genes: HERC3 KRT31 KRT40 PTPN11 PTPN6 SRC
Entrez ID		945
HPRD ID		01165
Ensembl ID		ENSG00000105383
Uniprot IDs		P20138 Q546G0
PDB IDs		5IHB 5J06 5J0B 6D48 6D49 6D4A
Enriched GO Terms of Interacting Partners?
Tagcloud ?