NEURL1

Description		neuralized E3 ubiquitin protein ligase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Cell Junction Dendritic Spine Perikaryon Perinuclear Region Of Cytoplasm Apical Dendrite
	Molecular Function	Ubiquitin-protein Transferase Activity Translation Factor Activity, Non-nucleic Acid Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Translation Protein Monoubiquitination Notch Signaling Pathway Sperm Axoneme Assembly Nervous System Development Brain Development Skeletal Muscle Tissue Development Lactation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Filopodium Assembly Positive Regulation Of Dendritic Spine Development Cellular Response To Amino Acid Stimulus Positive Regulation Of Synapse Maturation
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 28416822 30061737) Early onset atrial fibrillation ( 28460022) Incident atrial fibrillation ( 28416818) Intraocular pressure ( 29617998) Ischemic stroke (cardioembolic) ( 29531354) Prevalent atrial fibrillation ( 28416818) Response to antidepressants (symptom improvement) ( 29160301)
Interacting Genes		3 interacting genes: UBE2D1 UBE2H UBE2N
Entrez ID		9148
HPRD ID		04815
Ensembl ID		ENSG00000107954
Uniprot IDs		B4DS86 O76050
PDB IDs
Enriched GO Terms of Interacting Partners?
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