MBD4

Description		methyl-CpG binding domain 4, DNA glycosylase
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	DNA Binding Satellite DNA Binding Endodeoxyribonuclease Activity Protein Binding Pyrimidine-specific Mismatch Base Pair DNA N-glycosylase Activity DNA N-glycosylase Activity
	Biological Process	DNA Repair Response To Radiation Response To Estradiol Depyrimidination
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: CDCA2 CSNK2B DNMT3B FADD FAS HDAC1 KDM1A MLH1 SIN3A SUV39H1 TRIM27 UHRF1
Entrez ID		8930
HPRD ID		04654
Ensembl ID		ENSG00000129071
Uniprot IDs		O95243
PDB IDs		2MOE 3IHO 4DK9 4E9E 4E9F 4E9G 4E9H 4EA4 4EA5 4LG7 4OFA 4OFE 4OFH 5CHZ
Enriched GO Terms of Interacting Partners?
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