PLA2G10

Description		phospholipase A2 group X
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Phospholipase Activity Phospholipase A2 Activity Calcium Ion Binding Protein Binding Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Phosphatidic Acid Biosynthetic Process Axon Guidance Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Lipid Storage Lipid Catabolic Process Arachidonic Acid Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Prostaglandin Secretion Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Cholesterol Homeostasis Regulation Of Macrophage Activation Negative Regulation Of DNA-binding Transcription Factor Activity Arachidonic Acid Secretion Lysophospholipid Transport Positive Regulation Of Arachidonic Acid Secretion Negative Regulation Of Cholesterol Efflux Cellular Response To Leukemia Inhibitory Factor
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs		Varespladib methyl
Diseases
GWAS		Cholesteryl ester levels ( 31551469) Glycerophospholipid levels ( 26068415)
Interacting Genes		2 interacting genes: MYO10 PLA2R1
Entrez ID		8399
HPRD ID		04674
Ensembl ID		ENSG00000069764
Uniprot IDs		O15496
PDB IDs		1LE6 1LE7 4UY1 5G3M 5OW8 5OWC 6G5J
Enriched GO Terms of Interacting Partners?
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