HDAC10

Description		histone deacetylase 10
Image		No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Histone Deacetylase Activity Protein Binding Zinc Ion Binding Deacetylase Activity Enzyme Binding Protein Deacetylase Activity Histone Deacetylase Binding Acetylputrescine Deacetylase Activity Acetylspermidine Deacetylase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Chromatin Organization Regulation Of Transcription, DNA-templated Protein Deacetylation Oligodendrocyte Development Macroautophagy Histone Deacetylation Positive Regulation Of Mismatch Repair Peptidyl-lysine Deacetylation Homologous Recombination Negative Regulation Of Transcription, DNA-templated Polyamine Deacetylation Spermidine Deacetylation
Pathways		NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants HDACs deacetylate histones Notch-HLH transcription pathway
Drugs		Belinostat Panobinostat
Diseases
GWAS		Acne (severe) ( 24927181) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		8 interacting genes: HDAC2 HDAC3 HSPA8 MDC1 MTNR1A NCOR2 PAX3 TRIM28
Entrez ID		83933
HPRD ID		09407
Ensembl ID		ENSG00000100429
Uniprot IDs		Q969S8
PDB IDs
Enriched GO Terms of Interacting Partners?
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