PARP9

Description		poly(ADP-ribose) polymerase family member 9
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Membrane Protein-containing Complex Site Of DNA Damage
	Molecular Function	Transcription Corepressor Activity NAD+ ADP-ribosyltransferase Activity Enzyme Inhibitor Activity Protein Binding Enzyme Binding Histone Binding Ubiquitin-like Protein Ligase Binding NAD+ Binding ADP-D-ribose Binding STAT Family Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Defense Response To Virus By Host Double-strand Break Repair Protein ADP-ribosylation Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Migration NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Positive Regulation Of Chromatin Binding Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Catalytic Activity Innate Immune Response Positive Regulation Of Transcription, DNA-templated Defense Response To Virus Regulation Of Response To Interferon-gamma Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Protein Poly-ADP-ribosylation Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		Nicotinamide salvaging
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876) Total cholesterol levels ( 30275531)
Interacting Genes		1 interacting genes: DTX3L
Entrez ID		83666
HPRD ID		10686
Ensembl ID		ENSG00000138496
Uniprot IDs		Q59ER9 Q8IXQ6
PDB IDs		5AIL
Enriched GO Terms of Interacting Partners?
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